CaBLAM: High‑Contrast Bioluminescent Calcium Indicator (Update)
The revised CaBLAM manuscript is under review; the preprint details deep‑tissue, long‑duration imaging without external illumination.
Recent highlights from the Shaner Lab and collaborators
The revised CaBLAM manuscript is under review; the preprint details deep‑tissue, long‑duration imaging without external illumination.
Dr. Shaner presented strategies for mining marine biodiversity to develop next‑generation optical probes for neuroscience and cell biology.
Collaborative work with the St‑Pierre lab reports yellow fluorescent proteins with exceptional brightness and photostability for extended live‑cell imaging.
Talk on recent advances in fluorescent and bioluminescent tools, including published and upcoming technologies from the lab.
The UCSD Biosensor Core, managed by Dr. Shaner, offers consultation, curated biosensor collections, best‑practice coaching, and full‑service biosensor design.
Our team joins the Allen Discovery Center for Neurobiology in Changing Environments, leading biosensor curation and development across model species.
Seminar covering fluorescence and bioluminescence, genetically encoded indicators, optogenetics, and advanced imaging approaches.
Collaborative publications report FRET‑optimized bioluminescent control, improved luminopsins, and multi‑organ neuroimaging.
Opto/chemogenetic control · Luminopsin engineering · Multiorgan neuroimaging